Through the Exchange Management shell it is possible to set the domain controller to be used for the specific Exchange server.
To do this, open the EMS and type:
To view the current setting
Get-ADServerSettings | fl
To set the desired server instead type:
Set-ADServerSettings -PreferredServer dc2.exchangeserverpro.local
where dc2.exchangeserverpro.local is the FQDN of the domain controller eg. dc0.acs-hosting.local